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Article

[Activated protein C resistance: role in venous and arterial thrombosis].

Archives des maladies du coeur et des vaisseaux - 1 Jun 1996

Emmerich J, Alhenc-Gelas M, Aiach M, Fiessinger J N

Abstract excerpt

Activated protein C resistance is the most prevalent cause of thrombophilia: it is found in 20% to 30% of patients with a history of deep venous thrombosis history. Activated protein C resistance is due to an arginine 506 to glutamine mutation in factor V. This mutation prevents normal inactivation of activated factor V by activated protein C. The estimated increase in relative risk of venous thrombosis is 5 to...

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Identifiers

PMID: 8760661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Activated protein C resistance: role in venous and arterial thrombosis].PMID 8760661Read ↗

[Activated protein C resistance and factor V Leiden: clinical interest].Semantic proximity Read ↗

Resistance to activated protein C caused by a factor V gene mutation.Semantic proximity Read ↗

Activated protein C resistance: from phenotype to genotype and clinical practice.Semantic proximity Read ↗

[Activated protein C resistance as a cause of thrombophilia].Semantic proximity Read ↗

Activated protein C resistance--a major risk factor for thrombosis.Semantic proximity Read ↗

Activated protein C resistance: the most common risk factor for venous thromboembolism.Semantic proximity Read ↗

Activated protein C resistance as a basis for venous thrombosis.Semantic proximity Read ↗

Resistance to activated protein C caused by the factor VR506Q mutation is a common risk factor for venous thrombosis.Semantic proximity Read ↗

Activated protein C resistance due to a common factor V gene mutation is a major risk factor for venous thrombosis.Semantic proximity Read ↗

Resistance to activated protein C due to factor V R506Q mutation as a cause of venous thrombosis.Semantic proximity Read ↗

[Recently discovered frequent cause of venous thrombosis: factor V Leiden, a mutated factor V, resistant against protein C inactivation].Semantic proximity Read ↗

Inherited resistance to activated protein C, a major basis of venous thrombosis, is caused by deficient anticoagulant cofactor function of factor V.Semantic proximity Read ↗

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