[Activated protein C resistance: role in venous and arterial thrombosis].

Article

[Activated protein C resistance: role in venous and arterial thrombosis].

Archives des maladies du coeur et des vaisseaux - 1 Jun 1996

Emmerich J, Alhenc-Gelas M, Aiach M, Fiessinger J N

Abstract excerpt

Activated protein C resistance is the most prevalent cause of thrombophilia: it is found in 20% to 30% of patients with a history of deep venous thrombosis history. Activated protein C resistance is due to an arginine 506 to glutamine mutation in factor V. This mutation prevents normal inactivati...

Topics

Blood Coagulation Disorders
Drug Resistance
Factor V
Female
Genetic Predisposition to Disease
Humans
Male
Middle Aged
Point Mutation
Protein C
Thrombosis

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