Effects of nucleocapsid mutations on human immunodeficiency virus assembly and RNA encapsidation.

doi:10.1128/JVI.71.9.6765-6776.1997

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Article

Effects of nucleocapsid mutations on human immunodeficiency virus assembly and RNA encapsidation.

Journal of virology - 1 Sept 1997

Zhang Y, Barklis E

Abstract excerpt

The human immunodeficiency virus (HIV) Pr55Gag precursor proteins direct virus particle assembly. While Gag-Gag protein interactions which affect HIV assembly occur in the capsid (CA) domain of Pr55Gag, the nucleocapsid (NC) domain, which functions in viral RNA encapsidation, also appears to part...

Topics

Animals
COS Cells
Gene Products, gag
HIV-1
Humans
Mutation
Nucleocapsid
Protein Precursors
RNA, Viral
Virion
Virus Assembly
gag Gene Products, Human Immunodeficiency Virus

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