Article
Effects of nucleocapsid mutations on human immunodeficiency virus assembly and RNA encapsidation.
Journal of virology - 1 Sept 1997
Zhang Y, Barklis E
Abstract excerpt
The human immunodeficiency virus (HIV) Pr55Gag precursor proteins direct virus particle assembly. While Gag-Gag protein interactions which affect HIV assembly occur in the capsid (CA) domain of Pr55Gag, the nucleocapsid (NC) domain, which functions in viral RNA encapsidation, also appears to participate in virus assembly. In order to dissect the roles of the NC domain and the p6 domain, the C-terminal Gag protein...
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