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Article

Nucleocapsid-RNA interactions are essential to structural stability but not to assembly of retroviruses.

Journal of virology - 1 Jan 2004

Wang Shainn-Wei, Noonan Kristin, Aldovini Anna

Abstract excerpt

The process of RNA incorporation into nascent virions is thought to be critical for efficient retroviral particle assembly and production. Here we show that human immunodeficiency virus type 1 mutant particles (which are highly unstable and break down soon after release from the cell) lacking nucleocapsid (NC) core protein-mediated RNA incorporation are produced efficiently and can be recovered at the normal...

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Source

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Identifiers

PMID: 14694103
DOI: 10.1128/jvi.78.2.716-723.2004
PMCID: PMC368744

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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