Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNA incorporation is critical for retroviral particle integrity after cell membrane assembly of Gag complexes.

Journal of virology - 1 Dec 2002

Wang Shainn-Wei, Aldovini Anna

Abstract excerpt

The nucleocapsid (NC) domain of retroviruses plays a critical role in specific viral RNA packaging and virus assembly. RNA is thought to facilitate viral particle assembly, but the results described here with NC mutants indicate that it also plays a critical role in particle integrity. We investigated the assembly and integrity of particles produced by the human immunodeficiency virus type 1 M1-2/BR mutant virus,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Cell Membrane
Share to Gene Products, gag

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microscopy, Electron

Share to Nucleocapsid Proteins

Share to RNA, Viral

Share to Virus Assembly

Source

Open in PubMed Open full text

Identifiers

PMID: 12414928
DOI: 10.1128/jvi.76.23.11853-11865.2002
PMCID: PMC136867

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNA incorporation is critical for retroviral particle integrity after cell membrane assembly of Gag complexes.PMID 12414928Read ↗

Nucleocapsid-RNA interactions are essential to structural stability but not to assembly of retroviruses.Semantic proximity Read ↗

Redundant Roles for Nucleocapsid and Matrix RNA-Binding Sequences in Human Immunodeficiency Virus Type 1 AssemblySemantic proximity Read ↗

Murine leukemia virus nucleocapsid mutant particles lacking viral RNA encapsidate ribosomes.Semantic proximity Read ↗

Effects of nucleocapsid mutations on human immunodeficiency virus assembly and RNA encapsidation.Semantic proximity Read ↗

The C-Terminal Half of the Human Immunodeficiency Virus Type 1 Gag Precursor Is Sufficient for Efficient Particle AssemblySemantic proximity Read ↗

Analysis of minimal human immunodeficiency virus type 1 gag coding sequences capable of virus-like particle assembly and release.Semantic proximity Read ↗

Assembly, processing, and infectivity of human immunodeficiency virus type 1 gag mutantsSemantic proximity Read ↗

Basic residues in human immunodeficiency virus type 1 nucleocapsid promote virion assembly via interaction with RNA.Semantic proximity Read ↗

Nucleic Acid Binding by Mason-Pfizer Monkey Virus CA Promotes Virus Assembly and Genome Packaging.Semantic proximity Read ↗

Mutations in the Basic Region of the Mason-Pfizer Monkey Virus Nucleocapsid Protein Affect Reverse Transcription, Genomic RNA Packaging, and the Virus Assembly Site.Semantic proximity Read ↗

How HIV-1 Gag assembles in cells: Putting together pieces of the puzzle.Semantic proximity Read ↗

Characterization of human immunodeficiency virus type 1 Vif particle incorporationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.