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Article

Novel immunoglobulin superfamily gene cluster, mapping to a region of human chromosome 17q25, linked to psoriasis susceptibility.

Human genetics - 1 Jan 2003

Speckman Rebecca A, Wright Daw Jil A, Helms Cynthia, Duan Shenghui, Cao Li, Taillon-Miller Patricia, Kwok Pui-Yan, Menter Alan, Bowcock Anne M

Abstract excerpt

Chromosome 17q25 harbors a susceptibility locus for psoriasis ( PSORS2). This locus may overlap with loci for atopic dermatitis and rheumatoid arthritis. To further refine the location of PSORS2, we genotyped 242 primarily nuclear families for 15 polymorphic microsatellites mapping to chromosome 17q23-q25. Non-parametric linkage analysis revealed a linkage peak lying close to a novel cluster of genes from the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12483297
DOI: 10.1007/s00439-002-0851-y

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NPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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