Article
HLA-DM polymorphisms do not associate with multiple sclerosis: an association study with analysis of myelin basic protein T cell specificity.
Journal of neuroimmunology - 1 Aug 1997
Ristori G, Carcassi C, Lai S, Fiori P, Cacciani A, Floris L, Montesperelli C, Di Giovanni S, Buttinelli C, Contu L, Pozzilli C, Salvetti M
Abstract excerpt
The MHC region on 6p harbors at least one susceptibility gene for multiple sclerosis (MS). Within this region, HLA-DM loci are of interest being involved in class II antigen processing. We investigated the association of HLA-DM polymorphisms with MS. Sixty-three patients with MS and 46 healthy co...
Topics
- Adult
- Alleles
- Epitopes
- Female
- Gene Frequency
- HLA-D Antigens
- Histocompatibility Antigens Class II
- Histocompatibility Testing
- Humans
- Male
- Middle Aged
- Multiple Sclerosis
