Article
Multiple protein functions of paired in Drosophila development and their conservation in the Gooseberry and Pax3 homologs.
Development (Cambridge, England) - 1 Feb 2001
Xue L, Li X, Noll M
Abstract excerpt
The Drosophila segmentation gene paired, whose product is homologous to the Drosophila Gooseberry and mammalian Pax3 proteins, has three general functions: proper development of the larval cuticle, survival to adulthood and male fertility. Both DNA-binding domains, the conserved N-terminal paired-domain and prd-type homeodomain, are required within the same molecule for all general paired functions, whereas a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
