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Article

Evidence that the homeodomain protein Gtx is involved in the regulation of oligodendrocyte myelination.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Sept 1997

Awatramani R, Scherer S, Grinspan J, Collarini E, Skoff R, O'Hagan D, Garbern J, Kamholz J

Abstract excerpt

We have investigated the patterns of postnatal brain expression and DNA binding of Gtx, a homeodomain transcription factor. Gtx mRNA accumulates in parallel with the RNAs encoding the major structural proteins of myelin, myelin basic protein (MBP), and proteolipid protein (PLP) during postnatal brain development; Gtx mRNA decreases in parallel with MBP and PLP mRNAs in the brains of myelin-deficient rats, which...

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Identifiers

PMID: 9254678
PMCID: PMC6573154

Genes

MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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