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Article

A combinatorial network of evolutionarily conserved myelin basic protein regulatory sequences confers distinct glial-specific phenotypes.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 12 Nov 2003

Farhadi Hooman F, Lepage Pierre, Forghani Reza, Friedman Hana C H, Orfali Wayel, Jasmin Luc, Miller Webb, Hudson Thomas J, Peterson Alan C

Abstract excerpt

Myelin basic protein (MBP) is required for normal myelin compaction and is implicated in both experimental and human demyelinating diseases. In this study, as an initial step in defining the regulatory network controlling MBP transcription, we located and characterized the function of evolutionarily conserved regulatory sequences. Long-range human-mouse sequence comparison revealed over 1 kb of conserved...

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Identifiers

PMID: 14614079
PMCID: PMC6741010

Genes

MBP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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