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Article

Genetic control of interleukin 12 responsiveness: implications for disease pathogenesis.

Journal of molecular medicine (Berlin, Germany) - 1 Jul 1997

Gorham J D, Güler M L, Murphy K M

Abstract excerpt

We examined the effect of genetic background on Th1/Th2 development. We discuss data demonstrating that genetic background is an important determinant of interleukin-12 (IL-12) responsiveness and the potential implications for disease progression in murine experimental leishmaniasis. Genetic anal...

Topics

Animals
Disease Models, Animal
Disease Susceptibility
Gene Expression Regulation
Genetic Predisposition to Disease
Humans
Interleukin-12

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9253713
DOI: 10.1007/s001090050135

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9253713-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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