Antisense transcription occurs at the promoter of a mouse imprinted gene, commd1, on the repressed paternal allele.

doi:10.1093/jb/mvp147

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Antisense transcription occurs at the promoter of a mouse imprinted gene, commd1, on the repressed paternal allele.

Journal of biochemistry - 1 Dec 2009

Joh Keiichiro, Yatsuki Hitomi, Higashimoto Ken, Mukai Tsunehiro, Soejima Hidenobu

Abstract excerpt

The Commd1 gene is imprinted in the adult mouse brain and is predominantly expressed from the maternal allele. A paternally expressing imprinted gene, U2af1-rs1, resides in the first intron of Commd1 in an antisense orientation. We found that RNA polymerase II phosphorylated at serine 2 of the carboxyl-terminal domain repeats, a marker of transcription elongation, is enriched on the paternal allele than on the...

Topics

Adaptor Proteins, Signal Transducing
Alleles
Animals
Brain
DNA, Antisense
Genes, Y-Linked
Genomic Imprinting
Mice
Promoter Regions, Genetic
Proteins
Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 19762339
DOI: 10.1093/jb/mvp147

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics