Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Promoter of the Human Type I 5′‐Deiodinase Gene — Mapping of the Transcription Start Site and Identification of a DR+4 Thyroid‐Hormone‐Responsive Element

1 Jul 1997

Abstract excerpt

The selenoenzyme thyroxine 5'-deiodinase type I deiodinates the prohormone thyroxine to the active thyroid hormone 3,3',5-triiodothyronine. It is thus one of the key enzymes involved in the triiodothyronine-mediated control of growth, differentiation and basal metabolism in vertebrates. We report here the identification of the transcription start site and the cloning of 1500 bases of the upstream regulatory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Retinoids in leukemia and cellular processes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Thyroid Disorders and Treatments

Source

Identifiers

PMID: 9249039
DOI: 10.1111/j.1432-1033.1997.00288.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Promoter of the Human Type I 5′‐Deiodinase Gene — Mapping of the Transcription Start Site and Identification of a DR+4 Thyroid‐Hormone‐Responsive ElementPMID 9249039Read ↗

A Novel Retinoid X Receptor-Independent Thyroid Hormone Response Element Is Present in the Human Type 1 Deiodinase GeneSemantic proximity Read ↗

Pretranslational Regulation of Type 2 DeiodinaseSemantic proximity Read ↗

A novel cell type-specific mechanism for thyroid hormone-dependent negative regulation of the human type 1 deiodinase gene.Semantic proximity Read ↗

Deiodinases share an evolutionarily conserved thyroid hormone-binding motif.Semantic proximity Read ↗

Activation and inactivation of thyroid hormone by deiodinases: local action with general consequences.Semantic proximity Read ↗

Genomic imprinting of the type 3 thyroid hormone deiodinase gene: Regulation and developmental implicationsSemantic proximity Read ↗

Current concepts and challenges to unravel the role of iodothyronine deiodinases in human neoplasiasSemantic proximity Read ↗

Iodothyronine deiodinase structure and function: from ascidians to humans.Semantic proximity Read ↗

ABCD of Thyroid Hormone Action: After and Before Cloning of Deiodinase Genes.Semantic proximity Read ↗

Genetics in endocrinology: genetic variation in deiodinases: a systematic review of potential clinical effects in humans.Semantic proximity Read ↗

The 3′-Untranslated Region of Human Type 2 Iodothyronine Deiodinase mRNA Contains a Functional Selenocysteine Insertion Sequence ElementSemantic proximity Read ↗

The Human RC3 Gene Homolog, NRGN Contains a Thyroid Hormone-Responsive Element Located in the First Intron**This work was supported by grants from Fundacion Ramon Areces and DGICYT (PM95–0019).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.