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Article

Fibroblast growth factor 2 promotes tumor progression in an autochthonous mouse model of prostate cancer.

Cancer research - 15 Sept 2003

Polnaszek Nathaniel, Kwabi-Addo Bernard, Peterson Leif E, Ozen Mustafa, Greenberg Norman M, Ortega Sagrario, Basilico Claudio, Ittmann Michael

Abstract excerpt

Fibroblast growth factor (FGF) 2 (or basic FGF) is expressed at increased levels in human prostate cancer. FGF2 can promote cell motility and proliferation, increase tumor angiogenesis, and inhibit apoptosis, all of which play an important role in tumor progression. To determine whether FGF2 play...

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Source

Identifiers

PMID: 14522896

Genes

FGF2
FGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14522896-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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