Inhibition of growth of malignant rat prostate tumor cells by restoration of fibroblast growth factor receptor 2.

Article

Inhibition of growth of malignant rat prostate tumor cells by restoration of fibroblast growth factor receptor 2.

Cancer research - 1 Apr 1998

Matsubara A, Kan M, Feng S, McKeehan W L

Abstract excerpt

A loss of expression of fibroblast growth factor (FGF) receptor 2 IIIb (FGFR2IIIb), which responds to stroma-derived FGF, accompanies progression of premalignant androgen-responsive rat prostate tumor epithelial cells to the malignant phenotype. Concurrently, the level of FGFR2 gene expression is...

Topics

Animals
Cell Division
Male
Phenotype
Prostatic Neoplasms
Rats
Receptor Protein-Tyrosine Kinases
Receptor, Fibroblast Growth Factor, Type 2
Receptors, Fibroblast Growth Factor
Recombinant Fusion Proteins
Transfection

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