Article
Atopy, respiratory function and HLA-DR in Aboriginal Australians.
Human molecular genetics - 15 Mar 2003
Moffatt Miriam F, Faux Jennie A, Lester Susan, Paré Peter, McCluskey James, Spargo Randy, James Alan, Musk A William, Cookson William O C M
Abstract excerpt
The Class II genes of the MHC represent a major locus with quantified effects on atopic (allergic) phenotypes in many studies of westernized Caucasians. Although asthma is considered a disease of western societies, typical components of the asthma phenotype, such as elevations of the IgE, are seen with parasitic infestation. We have therefore investigated the effects of the HLA-DRB1 locus on asthma and its...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.