Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of activity of plasma platelet-activating factor acetylhydrolase due to a novel Gln281-->Arg mutation.

Biochemical and biophysical research communications - 30 Jul 1997

Yamada Y, Yokota M

Abstract excerpt

The prevalence of plasma platelet-activating factor (PAF) acetylhydrolase deficiency was investigated in 477 healthy Japanese individuals and 985 patients with various cardiovascular diseases. The genotype for this enzyme with regard to a G994-->T mutation (MM, normal; Mm, heterozygote; mm, mutant homozygote) was determined by an allele-specific polymerase chain reaction in 80 subjects shown to have no or low...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arginine
Share to Base Sequence
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Mutagenesis, Site-Directed

Share to Mutation

Share to Recombinant Proteins

Source

Identifiers

PMID: 9245731
DOI: 10.1006/bbrc.1997.7047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of activity of plasma platelet-activating factor acetylhydrolase due to a novel Gln281-->Arg mutation.PMID 9245731Read ↗

Identification of the G994--> T missense in exon 9 of the plasma platelet-activating factor acetylhydrolase gene as an independent risk factor for coronary artery disease in Japanese men.Semantic proximity Read ↗

Plasma platelet-activating factor acetylhydrolase deficiency is associated with atherosclerotic occlusive disease in japan.Semantic proximity Read ↗

A mutation in plasma platelet-activating factor acetylhydrolase (Val279-->Phe) is a genetic risk factor for stroke.Semantic proximity Read ↗

Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase.Semantic proximity Read ↗

Correlations between plasma platelet-activating factor acetylhydrolase (PAF-AH) activity and PAF-AH genotype, age, and atherosclerosis in a Japanese population.Semantic proximity Read ↗

A mutation in plasma platelet-activating factor acetylhydrolase (Val279Phe) is a genetic risk factor for cerebral hemorrhage but not for hypertension.Semantic proximity Read ↗

A single nucleotide polymorphism in the plasma PAF acetylhydrolase gene and risk of atherosclerosis in Japanese patients with peripheral artery occlusive disease.Semantic proximity Read ↗

Cellular source(s) of platelet-activating-factor acetylhydrolase activity in plasma.Semantic proximity Read ↗

Role of platelet-activating factor acetylhydrolase gene mutation in Japanese childhood IgA nephropathy.Semantic proximity Read ↗

Plasma platelet-activating factor acetylhydrolase deficiency in Japanese patients with asthma.Semantic proximity Read ↗

Platelet-activating factor acetylhydrolases in health and disease.Semantic proximity Read ↗

Association of a G994 -->T missense mutation in the plasma platelet-activating factor acetylhydrolase gene with risk of abdominal aortic aneurysm in Japanese.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.