Article
A single nucleotide polymorphism in the plasma PAF acetylhydrolase gene and risk of atherosclerosis in Japanese patients with peripheral artery occlusive disease.
The Journal of surgical research - 1 Jul 2006
Unno Naoki, Sakaguchi Takanori, Nakamura Toshio, Yamamoto Naoto, Sugatani Junko, Miwa Masao, Konno Hiroyuki
Abstract excerpt
BACKGROUND: Plasma PAF-acetylhydrolase (PAF-AH) gene polymorphisms (G994 --> T in exon 9) and the resulting deficiency of enzyme activity were identified in the Japanese population. The objective of this study was to assess the joint effect of the polymorphism and hypercholesterolemia on risk of atherosclerosis. METHODS AND RESULTS: We performed a case-control study including 150 patients who underwent operation...
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