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Article

Tracking changes in HIV-1 envelope quasispecies using DNA heteroduplex analysis.

Methods (San Diego, Calif.) - 1 Aug 1997

Delwart E L, Gordon C J

Abstract excerpt

A DNA heteroduplex tracking assay (HTA) using single-stranded probes is described. This assay provides a rapid means of resolving genetic variants coamplified by PCR and of measuring the level of particular variants in complex populations. To confidently detect minor quasispecies changes, the importance of maximizing template input into nested PCR (nPCR) and of duplicating nPCR and HTA to ensure correct...

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Share to DNA, Single-Stranded
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9245616
DOI: 10.1006/meth.1997.0489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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