Article
Viral genome characterisation by the heteroduplex mobility and heteroduplex tracking assays.
Reviews in medical virology - 1 Jan 2000
Barlow K L, Green J, Clewley J P
Abstract excerpt
The heteroduplex mobility assay (HMA) is a means of comparing two PCR amplicons or, in the variation known as the heteroduplex tracking assay (HTA), a means of estimating the quasispecies diversity of a viral genome. Heteroduplex assays have many applications including subtyping viral genomes, screening for low frequency variants in a population, scanning the relative genetic diversity across a genome and...
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