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Article

A novel denaturing heteroduplex tracking assay for genotypic prediction of HIV-1 tropism.

Journal of virological methods - 1 Oct 2012

Shi Binshan, Weiser Barbara, Styer Linda M, Kemal Kimdar, Brunner Cheryl, Anastos Kathryn, Burger Harold

Abstract excerpt

Human immunodeficiency virus type 1 (HIV-1) is characterized by sequence variability. The third variable region (V3) of the HIV-1 envelope glycoprotein gp120 plays a key role in determination of viral coreceptor usage (tropism) and pathogenesis. This report describes a novel denaturing heteroduplex tracking assay (HTA) to analyze the genetic variation of HIV-1 V3 DNA. It improved upon previous non-denaturing HTA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22728273
DOI: 10.1016/j.jviromet.2012.06.013
PMCID: PMC3417067

Genes

CCR5
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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