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Article

Measuring allelic heterogeneity in Plasmodium falciparum by a heteroduplex tracking assay.

The American journal of tropical medicine and hygiene - 1 Jun 2005

Ngrenngarmlert Warunee, Kwiek Jesse J, Kamwendo Deborah D, Ritola Kimberly, Swanstrom Ronald, Wongsrichanalai Chansuda, Miller R Scott, Ittarat Wanida, Meshnick Steven R

Abstract excerpt

We developed a novel Plasmodium falciparum genotyping strategy based on the heteroduplex tracking assay (HTA) method commonly used to genotype viruses. Because it can detect both sequence and size polymorphisms, we hypothesized that HTA is more sensitive than current methods. To test this hypothesis, we compared the ability of HTA and a nested polymerase chain reaction (PCR) to detect genetic diversity in 17 Thai...

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PMID: 15964952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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