Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human immunodeficiency virus type 1 evolution in vivo tracked by DNA heteroduplex mobility assays.

Journal of virology - 1 Oct 1994

Delwart E L, Sheppard H W, Walker B D, Goudsmit J, Mullins J I

Abstract excerpt

High mutation rates and strong selective pressures imposed on human immunodeficiency viruses in vivo result in the formation of pools of genetic variants known as quasispecies. DNA heteroduplex mobility and tracking analyses were used to monitor the generation of HIV sequence diversity, to estimate quasispecies complexity, and to assess the turnover of genetic variants to approach an understanding of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Biological Evolution
Share to DNA Primers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Viral

Share to Electrophoresis, Polyacrylamide Gel

Share to Molecular Sequence Data

Share to Mutation

Share to Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 8084001
DOI: 10.1128/JVI.68.10.6672-6683.1994
PMCID: PMC237088

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human immunodeficiency virus type 1 evolution in vivo tracked by DNA heteroduplex mobility assays.PMID 8084001Read ↗

Inferring viral population structures using heteroduplex mobility and DNA sequence analyses.Semantic proximity Read ↗

Slower evolution of human immunodeficiency virus type 1 quasispecies during progression to AIDS.Semantic proximity Read ↗

Genetic relationships determined by a DNA heteroduplex mobility assay: analysis of HIV-1 env genes.Semantic proximity Read ↗

Viral genome characterisation by the heteroduplex mobility and heteroduplex tracking assays.Semantic proximity Read ↗

Tracking changes in HIV-1 envelope quasispecies using DNA heteroduplex analysis.Semantic proximity Read ↗

Population genetic analysis of the protease locus of human immunodeficiency virus type 1 quasispecies undergoing drug selection, using a denaturing gradient-heteroduplex tracking assay.Semantic proximity Read ↗

Patterns of changes in human immunodeficiency virus type 1 V3 sequence populations late in infection.Semantic proximity Read ↗

Rapid molecular epidemiology of human immunodeficiency virus transmission.Semantic proximity Read ↗

Genetic characterization of rebounding human immunodeficiency virus type 1 in plasma during multiple interruptions of highly active antiretroviral therapy.Semantic proximity Read ↗

Sequential turnover of human immunodeficiency virus type 1 env throughout the course of infection.Semantic proximity Read ↗

Turnover of env variable region 1 and 2 genotypes in subjects with late-stage human immunodeficiency virus type 1 infection.Semantic proximity Read ↗

Different evolutionary patterns are found within human immunodeficiency virus type 1-infected patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.