Article
The yeast actin-related protein Arp2p is required for the internalization step of endocytosis.
Molecular biology of the cell - 1 Jul 1997
Moreau V, Galan J M, Devilliers G, Haguenauer-Tsapis R, Winsor B
Abstract excerpt
The Saccharomyces cerevisiae actin-related protein Arp2p is an essential component of the actin cytoskeleton. We have tested its potential role in the endocytic and exocytic pathways by using a temperature-sensitive allele, arp2-1. The fate of the plasma membrane transporter uracil permease was followed to determine whether Arp2p plays a role in the endocytic pathway. Inhibition of normal endocytosis as revealed...
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