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Article

Genetic heterogeneity in supratentorial and infratentorial primitive neuroectodermal tumours of the central nervous system

22 Nov 2005

Abstract excerpt

AIMS: Medulloblastoma (MB), a kind of infratentorial primitive neuroectodermal tumour (PNET), is the most frequent malignant brain tumour in childhood. In contrast, supratentorial PNET (sPNET) are very infrequent tumours, but they are histologically similar to MB, although they present a worse clinical outcome. We investigated the differences in genetic abnormalities between sPNET and MB. METHODS AND RESULTS: We...

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PMID: 16324202
DOI: 10.1111/j.1365-2559.2005.02304.x

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