Article
Both apolipoprotein E and A-I genes are present in a nonmammalian vertebrate and are highly expressed during embryonic development
5 Aug 1997
Abstract excerpt
Apolipoprotein E (apoE) is associated with several classes of plasma lipoproteins and mediates uptake of lipoproteins through its ability to interact with specific cell surface receptors. Besides its role in cardiovascular diseases, accumulating evidence has suggested that apoE could play a role in neurodegenerative diseases, such as Alzheimer disease. In vertebrates, apoA-I is the major protein of high-density...
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