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Apolipoprotein E and the Apolipoprotein E-Deficient Mouse

1 Jul 1995

Abstract excerpt

Apolipoprotein E (apoE) is one of several lipoprotein transfer genes. A primary function of this protein is the mediation of receptor-mediated lipoprotein removal from the blood. Several studies have demonstrated that genetic variation at the apoE locus is associated with an increased risk of developing atherosclerosis, and recent studies implicate this same genetic variation in determining susceptibility to...

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PMID: 8527231
DOI: 10.1146/annurev.nu.15.070195.002431

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