Article
The LDL receptor gene family, apolipoprotein B and cholesterol in embryonic development.
The Journal of nutrition - 1 Feb 1999
Herz J, Farese R V
Abstract excerpt
In recent years, a number of genes that are involved in cholesterol synthesis, its systemic or intercellular transport or lipid metabolism in general have been found to play important roles during embryonic development. In this article, we present a brief overview of these genes, their molecular functions as we understand them to date and our current interpretation of possible mechanisms by which genetic...
Topics
- Animals
- Apolipoproteins B
- Carrier Proteins
- Cholesterol
- Embryonic and Fetal Development
- Humans
- Mutation
- Receptors, LDL