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Article

Conserved protein motifs and structural organization of a fish gene homologous to mammalian apolipoprotein E

1 Jan 2000

Abstract excerpt

Apolipoprotein E (apoE) plays a central role in lipid metabolism from its ability to interact with lipoprotein receptors. Besides its role in cardiovascular diseases, apoE polymorphism contributes to susceptibility to neurodegenerative diseases, such as Alzheimer's disease. The statistical significance of the combined match scores obtained after apoE motif-based protein sequence database searches, the structural...

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PMID: 10632725
DOI: 10.1046/j.1432-1327.2000.01033.x

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