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Article

Tumor Necrosis Factor Promoter Polymorphism and Susceptibility to Lepromatous Leprosy

1 Aug 1997

Abstract excerpt

Genetically determined differences in immune responses to environmental agents may underlie susceptibility to many autoimmune and infectious diseases. Leprosy provides an example of a polarity in the type of immune response made to an infectious agent, and there is evidence that the major histocompatibility complex is genetically linked to leprosy type. It was found that HLA-DR2 is associated with both...

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PMID: 9237725
DOI: 10.1086/517282

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