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Article

Mutation of a TADR protein leads to rhodopsin and Gq-dependent retinal degeneration in Drosophila.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 10 Dec 2008

Ni Lina, Guo Peiyi, Reddig Keith, Mitra Mirna, Li Hong-Sheng

Abstract excerpt

The Drosophila photoreceptor is a model system for genetic study of retinal degeneration. Many gene mutations cause fly photoreceptor degeneration, either because of excessive stimulation of the visual transduction (phototransduction) cascade, or through apoptotic pathways that in many cases involve a visual arrestin Arr2. Here we report a gene named tadr (for torn and diminished rhabdomeres), which, when...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to GTP-Binding Protein alpha Subunits, Gq-G11

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Source

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Identifiers

PMID: 19074021
DOI: 10.1523/JNEUROSCI.2122-08.2008
PMCID: PMC2630459

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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