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Article

Homeosis and polyposis: a tale from the mouse.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jul 1997

He T C, da Costa L T, Thiagalingam S

Abstract excerpt

Homeobox genes play essential roles in specifying the fates of different cell types during embryogenesis. In Drosophila, the homeotic gene caudal is important for the generation of posterior structures. In the mouse, the caudal homologue Cdx2 has been implicated in directing early processes in intestinal morphogenesis and in the maintenance of the differentiated phenotype. A recent study showed that Cdx2 null...

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PMID: 9230687
DOI: 10.1002/bies.950190705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Homeosis and polyposis: a tale from the mouse.PMID 9230687Read ↗

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The clinical perspectives of CDX2 expression in colorectal cancer: a qualitative systematic review.Semantic proximity Read ↗

The <i>Cdx2</i> homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut developmentSemantic proximity Read ↗

CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer.Semantic proximity Read ↗

The Lineage-Specific Transcription Factor CDX2 Navigates Dynamic Chromatin to Control Distinct Stages of Intestine DevelopmentSemantic proximity Read ↗

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