Mechanistic insights from biomarker studies: somatic mutations and rodent/human comparisons following exposure to a potential carcinogen.

Abstract excerpt

The field of cancer molecular epidemiology is maturing rapidly. There is a vast armamentarium of biomarkers that is now used to assess human exposures to environmental carcinogens, the non-cancer effects of the exposures, and individual susceptibilities. There is also widespread realization that biomarkers must be validated before they are useful for human studies. One of the objectives of molecular epidemiology...

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