Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Relevance of Carcinogen-Induced Preclinical Cancer Models

5 Jan 2024

Abstract excerpt

Chemical agents can cause cancer in animals by damaging their DNA, mutating their genes, and modifying their epigenetic signatures. Carcinogen-induced preclinical cancer models are useful for understanding carcinogen-induced human cancers, as they can reproduce the diversity and complexity of tumor types, as well as the interactions with the host environment. However, these models also have some drawbacks that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer, Stress, Anesthesia, and Immune Response
Share to Genomics, phytochemicals, and oxidative stress

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38249103
DOI: 10.3390/jox14010006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Relevance of Carcinogen-Induced Preclinical Cancer ModelsPMID 38249103Read ↗

Mammalian models of chemically induced primary malignancies exploitable for imaging-based preclinical theragnostic research.Semantic proximity Read ↗

A Review of the Molecular Mechanisms of Chemically Induced Neoplasia in Rat and Mouse Models in National Toxicology Program Bioassays and Their Relevance to Human CancerSemantic proximity Read ↗

Modernizing Human Cancer Risk Assessment of Therapeutics.Semantic proximity Read ↗

Progress of non-human primate animal models of cancers.Semantic proximity Read ↗

Mechanism-Based Cancer Prevention Approaches: Targets, Examples, and the Use of Transgenic MiceSemantic proximity Read ↗

Past, present, and future of chemically induced hepatocarcinogenesis rodent models: Perspectives concerning classic and new cancer hallmarksSemantic proximity Read ↗

Organoids in recapitulating tumorigenesis driven by risk factors: Current trends and future perspectivesSemantic proximity Read ↗

Preventable Exposures Associated With Human CancersSemantic proximity Read ↗

Chemically induced skin carcinogenesis: Updates in experimental models (Review)Semantic proximity Read ↗

Mechanisms of multistep carcinogenesis and carcinogen risk assessment.Semantic proximity Read ↗

The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure ThemSemantic proximity Read ↗

Development of human cell models for assessing the carcinogenic potential of chemicalsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.