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Article

Prenatal determination of genotypes Kell and Cellano in at-risk pregnancies.

The Journal of reproductive medicine - 1 Jun 1997

Spence W C, Maddalena A, Demers D B, Bick D P

Abstract excerpt

OBJECTIVE: To evaluate the accuracy of a DNA-based testing methodology in determining the KEL1 and KEL2 (Kell and Cellano) genotype of fetuses at risk for Kell or Cellano hemolytic disease. STUDY DESIGN: DNA was extracted from chorionic villus samples (CVS) or amniotic fluid (AF) cells, a portion of the Kell gene was amplified, the amplified product was cut with a restriction enzyme that recognizes the KEL1...

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PMID: 9219123

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