Genotyping of KEL1 and KEL2 of the human Kell blood group system by the polymerase chain reaction with sequence-specific primers.

doi:10.1046/j.1537-2995.1996.36696269506.x

Back to search

Article

Genotyping of KEL1 and KEL2 of the human Kell blood group system by the polymerase chain reaction with sequence-specific primers.

Transfusion - 1 Jun 1996

Hessner M J, McFarland J G, Endean D J

Abstract excerpt

BACKGROUND: Kell is a major antigenic system in human red cells, with more than 20 identified antigens. KEL1 and KEL2 are two opposing low- and high-frequency alleles. Immunization to KEL1 is clinically significant, because anti-KEL1 can cause severe reactions to transfusion of incompatible blood...

Topics

Alleles
Base Sequence
DNA
DNA Primers
Genotype
Growth Hormone
Humans
Kell Blood-Group System
Molecular Sequence Data
Polymerase Chain Reaction

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.