Article
Noninvasive diagnostics of fetal KEL*01.01 allele from maternal plasma of immunized women using digital PCR protocols.
Transfusion - 1 Apr 2022
Orzińska Agnieszka, Krzemienowska Magdalena, Purchla-Szepioła Sylwia, Kopeć Izabella, Guz Katarzyna
Abstract excerpt
Allo-antibodies produced by K-negative pregnant women against a fetal K antigen from the Kell blood group system may cause hemolytic disease of the fetus and newborn (HDFN). Predicting the fetal K antigen using noninvasive prenatal testing (NIPT) is important for decisions concerning management of pregnancies. Digital and droplet digital PCR techniques permit the detection of fetal single nucleotide variant with...
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