Article
Next-generation sequencing: proof of concept for antenatal prediction of the fetal Kell blood group phenotype from cell-free fetal DNA in maternal plasma.
Transfusion - 1 Nov 2013
Rieneck Klaus, Bak Mads, Jønson Lars, Clausen Frederik Banch, Krog Grethe Risum, Tommerup Niels, Nielsen Leif Kofoed, Hedegaard Morten, Dziegiel Morten Hanefeld
Abstract excerpt
BACKGROUND: Maternal immunization against KEL1 of the Kell blood group system can have serious adverse consequences for the fetus as well as the newborn baby. Therefore, it is important to determine the phenotype of the fetus to predict whether it is at risk. We present data that show the feasibility of predicting the fetal KEL1 phenotype using next-generation sequencing (NGS) technology. STUDY DESIGN AND...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.