Article
Preimplantation genetic diagnosis for the Kell genotype.
Fertility and sterility - 1 Oct 2003
Verlinsky Yury, Rechitsky Svetlana, Ozen Seckin, Masciangelo Christina, Ayers Jonathan, Kuliev Anver
Abstract excerpt
OBJECTIVE: To use preimplantation genetic diagnosis (PGD) to achieve a Kell 1 (K1) allele-free pregnancy in couples at risk for producing a child with hemolytic disease of the newborn (HDN) caused by maternofetal incompatibility in sensitized mothers. DESIGN: DNA analysis of biopsied blastomeres from cleavage-stage embryos in IVF-ET with the goal of identifying and transferring back to patients the K1 allele-free...
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