Article
An innovative test for non-invasive Kell genotyping on circulating fetal DNA by means of the allelic discrimination of K1 and K2 antigens.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Dec 2016
Cro' Fabiana, Lapucci Cristina, Vicari Emilio, Salsi Ginevra, Rizzo Nicola, Farina Antonio
Abstract excerpt
OBJECTIVE: The aim of this study was to present a new method for fetal Kell genotyping by means of the allelic discrimination of K1 and K2 in real-time polymerase chain reaction (PCR). METHODS: Real-time quantitative polymerase chain reaction incorporating an allele-specific primer was developed for detecting the K allele of KEL. RESULTS: By means of this method, the K1/K2 genotype was able to be determined in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
