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Article

Clastogenicity and mutagenicity of hexavalent chromium in lacZ transgenic mice.

Toxicology letters - 16 May 1997

Itoh S, Shimada H

Abstract excerpt

The clastogenic and mutagenic effects of the hexavalent chromium compound K2CrO4 in lacZ transgenic mice (Muta Mouse) were investigated. Male Muta mice were administered an intraperitoneal dose of 40 mg/kg of K2CrO4 once on each of 2 consecutive days. The K2CrO4 induced a significant increase in the peripheral blood micronucleated reticulocyte count. Also, K2CrO4 induced a statistically significant increase in...

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PMID: 9217243
DOI: 10.1016/s0378-4274(97)00026-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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