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Article

Induction of lacZ mutation by 7,12-dimethylbenz[a]anthracene in various tissues of transgenic mice.

Mutation research - 18 Aug 1999

Hachiya N, Yajima N, Hatakeyama S, Yuno K, Okada N, Umeda Y, Wakata A, Motohashi Y

Abstract excerpt

The induction of gene mutations was examined in MutaMouse after an intraperitoneal injection of 7, 8-dimethylbenz[a]anthracene (DMBA) at 20 mg/kg in a collaborative study participated by four laboratories. Although the DMBA dose used was lower than the level that has been reported to induce micronucleated erythrocytes maximally in several mouse strains, a killing effect appeared after day 9 of the post-treatment...

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Source

Identifiers

PMID: 10521669
DOI: 10.1016/s1383-5718(99)00063-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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