Article
Deletions at stalled replication forks occur by two different pathways.
The EMBO journal - 2 Jun 1997
Bierne H, Ehrlich S D, Michel B
Abstract excerpt
Replication blockage induces non-homologous deletions in Escherichia coli. The mechanism of the formation of these deletions was investigated. A pBR322-mini-oriC hybrid plasmid carrying two E. coli replication terminators (Ter sites) in opposite orientations was used. Deletions which remove at least the pBR322 blocking site (named Ter1) occurred at a frequency of 2 x 10(-6) per generation. They fall into two...
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