Enhanced deletion formation by aberrant DNA replication in Escherichia coli.

doi:10.1093/genetics/146.2.457

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Article

Enhanced deletion formation by aberrant DNA replication in Escherichia coli.

Genetics - 1 Jun 1997

Saveson C J, Lovett S T

Abstract excerpt

Repeated genes and sequences are prone to genetic rearrangements including deletions. We have investigated deletion formation in Escherichia coli strains mutant for various replication functions. Deletion was selected between 787 base pair tandem repeats carried either on a ColE1-derived plasmid...

Topics

Bacteriocin Plasmids
Chromosomes, Bacterial
DNA Polymerase III
DNA Replication
DNA, Single-Stranded
Escherichia coli
Genes, Bacterial
Genotype
Models, Genetic
Mutation
Rec A Recombinases
Repetitive Sequences, Nucleic Acid
SOS Response, Genetics
Sequence Deletion

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