Detection of archetype and rearranged variants of JC virus in multiple tissues from a pediatric PML patient.

doi:10.1002/(sici)1096-9071(199707)52:3<243::aid-jmv2>3.0.co;2-2

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Article

Detection of archetype and rearranged variants of JC virus in multiple tissues from a pediatric PML patient.

Journal of medical virology - 1 Jul 1997

Newman J T, Frisque R J

Abstract excerpt

JC virus (JCV) establishes persistent infections in its human host, and in some immunocompromised individuals, the virus causes the fatal brain disease progressive multifocal leukoencephalopathy (PML). Two forms of the virus, archetype and rearranged, have been isolated, with the latter being der...

Topics

Child
DNA, Viral
Gene Rearrangement
Genetic Variation
Humans
JC Virus
Leukoencephalopathy, Progressive Multifocal
Papillomavirus Infections
Severe Combined Immunodeficiency
Tumor Virus Infections

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