Article
Detection of archetype and rearranged variants of JC virus in multiple tissues from a pediatric PML patient.
Journal of medical virology - 1 Jul 1997
Newman J T, Frisque R J
Abstract excerpt
JC virus (JCV) establishes persistent infections in its human host, and in some immunocompromised individuals, the virus causes the fatal brain disease progressive multifocal leukoencephalopathy (PML). Two forms of the virus, archetype and rearranged, have been isolated, with the latter being derived from the archetype form by deletion and duplication of sequences within the viral transcriptional control region...
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