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JC virus DNA is present in many human brain samples from patients without progressive multifocal leukoencephalopathy

1 Oct 1992

Abstract excerpt

Sections of normal and diseased brain and kidney tissues were screened for the presence of JC virus (JCV) DNA by using the polymerase chain reaction. As expected, all samples obtained from patients with progressive multifocal leukoencephalopathy (PML) tested positive when multiple JCV-specific primer and probe combinations were used. Unexpectedly, more than 50% of non-PML-affected brains were also found to harbor...

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Identifiers

PMID: 1326640
DOI: 10.1128/jvi.66.10.5726-5734.1992

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