Article
Cell-free transmission of Fv-4 resistance gene product controlling Friend leukemia virus-induced leukemogenesis in mice.
Leukemia - 1 Apr 1997
Kitagawa M, Aizawa S, Ikeda H, Hirokawa K
Abstract excerpt
Fv-4 is a mouse gene that dominantly confers resistance to infection by ecotropic murine leukemia virus (MuLV). The Fv-4' env antigen that binds to the cell surface of Fv-4'-bearing C3H cells was found in sera from normal Fv-4'-bearing C4W mice. The serum Fv-4' env antigen binds to ecotropic MuLV...
Topics
- Animals
- Antigens, Viral
- Friend murine leukemia virus
- Gene Products, env
- Genetic Predisposition to Disease
- Immunity, Innate
- Leukemia, Experimental
- Lymphocytes
- Membrane Proteins
- Mice
- Mice, Inbred C3H
- Receptors, Virus
- Retroviridae Infections
- Spleen
- Thymus Gland
- Tumor Virus Infections
