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Article

Antigenic subclasses of polytropic murine leukemia virus (MLV) isolates reflect three distinct groups of endogenous polytropic MLV-related sequences in NFS/N mice.

Journal of virology - 1 Oct 2003

Evans Leonard H, Lavignon Marc, Taylor Marc, Alamgir A S M

Abstract excerpt

Polytropic murine leukemia viruses (MLVs) are generated by recombination of ecotropic MLVs with members of a family of endogenous proviruses in mice. Previous studies have indicated that polytropic MLV isolates comprise two mutually exclusive antigenic subclasses, each of which is reactive with one of two monoclonal antibodies termed MAb 516 and Hy 7. A major determinant of the epitopes distinguishing the...

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Identifiers

PMID: 12970417
DOI: 10.1128/jvi.77.19.10327-10338.2003
PMCID: PMC228382

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