Article
A novel polymorphic cytochrome P450 formed by splicing of CYP3A7 and the pseudogene CYP3AP1.
The Journal of biological chemistry - 5 Aug 2005
Rodriguez-Antona Cristina, Axelson Magnus, Otter Charlotta, Rane Anders, Ingelman-Sundberg Magnus
Abstract excerpt
The cytochrome P450 3A7 (CYP3A7) is the most abundant CYP in human liver during fetal development and first months of postnatal age, playing an important role in the metabolism of endogenous hormones, drugs, differentiation factors, and potentially toxic and teratogenic substrates. Here we descri...
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