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Article

The SH3 domain of Bruton's tyrosine kinase interacts with Vav, Sam68 and EWS.

Scandinavian journal of immunology - 1 Jun 1997

Guinamard R, Fougereau M, Seckinger P

Abstract excerpt

Bruton tyrosine kinase (BTK) is a cytoplasmic protein tyrosine kinase which controls crucial steps of differentiation of B lymphocytes. Mutations affecting either the PH, SH3, SH2 or kinase domain of BTK all give rise to X linked agammaglobulinaemia (XLA) in humans. In this study, the authors report that the BTK-SH3 domain binds to a set of proteins expressed in pro-B, pre-B and B cell lines. Three of them were...

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Source

Identifiers

PMID: 9201297
DOI: 10.1046/j.1365-3083.1997.d01-447.x

Genes

BTK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The SH3 domain of Bruton's tyrosine kinase interacts with Vav, Sam68 and EWS.PMID 9201297Read ↗

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Signalling of Bruton's Tyrosine Kinase, BtkSemantic proximity Read ↗

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