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Article

Bruton tyrosine kinase (BTK) in X-linked agammaglobulinemia (XLA).

Frontiers in bioscience : a journal and virtual library - 1 Dec 2000

Vihinen M, Mattsson P T, Smith C I

Abstract excerpt

X-linked agammaglobulinemia (XLA) is a heritable immunodeficiency disorder that is caused by a differentiation block leading to almost complete absence of B lymphocytes and plasma cells. The affected protein is a cytoplasmic protein tyrosine kinase, Bruton's agammaglobulinemia tyrosine kinase (Btk). Btk along with Tec, Itk, Bmx and Txk belong to a distinct family of protein kinases. These proteins contain five...

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Source

Identifiers

PMID: 11102316
DOI: 10.2741/vihinen

Genes

BTK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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